Dr. Tsuji has led TU’s Diet & Cancer Lab since 2011. Our laboratory primarily investigates the molecular mechanisms of colon cancer and inflammation. In particular, the use of dietary compounds as preventive strategies are of interest. This includes but is not limited to the trace mineral Selenium, select polyphenols, and extracts generated from Sorghum bicolor. Biological models utilized include in vitro (human and mouse cells) and in vivo (mouse) models.
Additional interests include the intestinal/fecal microbiome of mammals. For example, we investigate the effects of seasonal dietary changes on the relative abundance of microbiota in a variety of mammals (e.g., polar bears, African elephants). This is in collaboration with faculty in the Department of Chemistry & Forensic Science.
We are truly passionate about training the next generation of scientists, and we train undergraduate and graduate students in basic and advanced molecular biology techniques, academic integrity, and lab citizenship. Interested student should read the ‘Research Opportunities’ page and contact Dr. Tsuji or one of her students for more information.
Our goals:
1) Produce sound science. The results of our experiments, when done accurately, will be submitted for publication in scientific journals that help to elucidate molecular mechanisms of dietary nutrients in health and disease. Our success as scientists is measured by the contributions we make to knowledge in the form of publications. Thus, experiments will be planned and executed carefully.
2) Train undergraduate and graduate students in molecular biology techniques and, specifically, in concepts of nutrients and cancer prevention. Mentor-trainee and peer learning are both valuable training and learning opportunities. Training also includes lab citizenship, academic and research integrity. High expectations are the norm, not the exception.
3) Community. As a part of the scientific community, we strive to provide the general public with useful scientific knowledge that leads to better health outcomes. We also build an intentional support network within our lab and with extended internal and external relationships.
